The SLC4A7 Polyclonal Antibody (CAB10271) is a crucial tool for research involving the SLC4A7 protein, a member of the SLC4 bicarbonate transporter family. This antibody, generated using rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SLC4A7 protein, this antibody enables the detection and analysis of SLC4A7 in various cell types, making it an ideal choice for studies in physiology and drug development.SLC4A7, also known as NBCn1, plays a key role in regulating intracellular pH and ion transport in various tissues, with implications in diseases such as cancer, hypertension, and neurological disorders.
Understanding the function and regulation of SLC4A7 is essential for developing targeted therapies that modulate ion transport and pH regulation in diseased states.By utilizing the SLC4A7 Polyclonal Antibody (CAB10271), researchers can gain valuable insights into the role of SLC4A7 in cellular physiology and disease pathology, ultimately contributing to the development of innovative treatments for a range of conditions.
Product Name:
SLC4A7 Rabbit Polyclonal Antibody
SKU:
CAB10271
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1151-1214 of human SLC4A7 (NP_003606.3).
This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
9497
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse liver, using SLC4A7 antibody (CAB10271) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
