The SLC4A2 Antibody (CAB7729) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.SLC4A2, also known as the sodium bicarbonate cotransporter 2 (NBCe1), plays a crucial role in maintaining cellular pH balance and electrolyte transport. Dysregulation of SLC4A2 has been linked to various human diseases, including renal tubular acidosis and neurological disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
SLC4A2 Antibody
SKU:
CAB7729
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
AE2, HKB3, BND3L, NBND3, EPB3L1, SLC4A2
Positive Sample:
HeLa, A-549, Jurkat, HT-29
Cellular Localization:
Membrane, Multi-Pass Membrane Protein.
Calculated MW:
137kDa
Observed MW:
140kDa
This gene encodes a member of the anion exchanger family of membrane transport proteins. The encoded protein regulates intracellular pH, biliary bicarbonate secretion, and chloride uptake. Reduced expression of this gene may be associated with primary biliary cirrhosis (PBC) in human patients, while differential expression of this gene may be associated with malignant hepatocellular carcinoma, colon and gastric cancers.
Purification Method
Affinity purification
Gene ID
6522
RRID
AB_2772280
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC4A2 Rabbit pAb (CAB7729) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
