The SLC47A1 Polyclonal Antibody (CAB14559) is a vital tool for researchers studying SLC47A1, a crucial transporter protein involved in the uptake and efflux of various organic cations across cell membranes. This polyclonal antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.SLC47A1, also known as Multidrug and Toxin Extrusion Protein 1 (MATE1), plays a significant role in drug pharmacokinetics and drug-drug interactions by mediating the transport of various therapeutic drugs and endogenous compounds.
Its role in drug transport and cellular homeostasis makes it a key target for research in pharmacology, toxicology, and personalized medicine.By utilizing the SLC47A1 Polyclonal Antibody, researchers can effectively detect and analyze the expression of SLC47A1 protein in different cell types and tissues, providing valuable insights into its functions and potential implications in drug response and toxicity. This antibody is an essential tool for advancing our understanding of drug transport mechanisms and developing targeted therapies for a range of diseases and conditions.
Product Name:
SLC47A1 Rabbit Polyclonal Antibody
SKU:
CAB14559
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 460-550 of human SLC47A1 (NP_060712.2).
This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function.
Purification Method:
Affinity purification
Gene ID:
55244
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat liver, using SLC47A1 Rabbit pAb (CAB14559) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
