The SLC46A2 Polyclonal Antibody (CAB15494) is designed for research involving SLC46A2, a membrane protein involved in the transport of small solutes, such as folate, across cell membranes. The antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blot and immunofluorescence.SLC46A2, also known as proton-coupled folate transporter (PCFT), plays a crucial role in folate homeostasis and is essential for folate uptake in the intestine and in cells that rely on folate for growth and survival. Dysregulation of SLC46A2 has been implicated in various disorders, including cancer and folate deficiency-related conditions.
Understanding the function and regulation of SLC46A2 is important for developing strategies to modulate folate levels and improve health outcomes.This high-quality polyclonal antibody targets the SLC46A2 protein, providing researchers with a valuable tool for studying folate transport mechanisms and exploring the role of SLC46A2 in health and disease. Its specificity and reliability make it an ideal choice for immunology, nutrition, and cancer research studies.
Product Name:
SLC46A2 Rabbit Polyclonal Antibody
SKU:
CAB15494
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SLC46A2 (NP_149040.3).
Predicted to enable transmembrane transporter activity. Involved in positive regulation of nucleotide-binding activity oligomerization domain containing 1 signaling pathway. Predicted to be located in cell surface and plasma membrane. Predicted to be integral component of membrane.
Purification Method:
Affinity purification
Gene ID:
57864
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC46A2 Rabbit pAb (CAB15494) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
