The SLC45A3 Polyclonal Antibody (PAC020183) is a valuable tool for researchers studying SLC45A3, a protein involved in melanin synthesis and skin pigmentation. This antibody, produced in rabbits, specifically binds to SLC45A3 and is highly reactive with human samples, making it ideal for use in Western blot applications. With the ability to detect and analyze SLC45A3 in various cell types, this antibody is essential for investigations in dermatology, genetics, and cancer research.SLC45A3, also known as membrane-associated transporter protein (MATP), plays a crucial role in melanin production by transporting melanin precursors to melanosomes in melanocytes.
Its function in skin pigmentation makes it a key target for studies on pigmentation disorders, skin cancer, and genetic variations in melanin synthesis. Understanding the mechanisms and regulation of SLC45A3 is essential for developing treatments and interventions for diseases related to melanin production and skin coloration.
Antibody Name:
SLC45A3 Antibody (PACO20183)
Antibody SKU:
PACO20183
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:1000-1:2000, WB:1:200-1:1000
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human SLC45A3
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane: Human fetal brain tissue, Primary antibody: PACO20183(SLC45A3 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes.
Background:
Solute carrier family 45 member 3 (SLC45A3), also known as prostate cancer-associated protein 6 or prostein, is a protein that in humans is encoded by theSLC45A3 gene. SLC45A3 is expressed in a prostate-specific manner by normal tissues and at a significantly lower level in prostate tumor cell lines. Treatment prostate cancer cell lines with androgens upregulates the expression of SLC45A3.
Synonyms:
solute carrier family 45, member 3
UniProt Protein Function:
SLC45A3: Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family.Protein type: Cell surface; Enzyme, misc.; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 1q32.1Molecular Function: sucrose:hydrogen symporter activityBiological Process: positive regulation of fatty acid biosynthetic process; regulation of oligodendrocyte differentiation; sucrose transport
