The SLC44A4 Polyclonal Antibody (CAB10435) is an essential tool for researchers studying SLC44A4, a key protein involved in cellular transport processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting SLC44A4 in human samples, making it ideal for use in Western blot applications. By binding to SLC44A4, the antibody enables accurate and reliable analysis of this protein in various cell types, offering valuable insights for studies in cell biology and pharmacology.SLC44A4, also known as the choline transporter-like protein 4, plays a crucial role in the transport of choline, an essential nutrient involved in various physiological functions such as neurotransmission and membrane synthesis.
Dysregulation of SLC44A4 has been implicated in diseases like cancer and metabolic disorders, highlighting its significance as a potential therapeutic target. By investigating the function and expression of SLC44A4, researchers can gain a deeper understanding of its role in disease pathogenesis and potentially develop novel treatment strategies targeting this transporter protein.
Product Name:
SLC44A4 Rabbit Polyclonal Antibody
SKU:
CAB10435
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 65-215 of human SLC44A4 (NP_079533.2).
The protein encoded by this gene may be a sodium-dependent transmembrane transport protein involved in the uptake of choline by cholinergic neurons. Defects in this gene can cause sialidosis, a lysosomal storage disease. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
80736
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SLC44A4 antibody (CAB10435) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
