The SLC43A3 Antibody (PAC039950) is a key tool for researchers studying the SLC43A3 protein, which plays a vital role in amino acid transport across cell membranes. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.SLC43A3 is a member of the SLC43 family of solute carriers, involved in the transport of essential amino acids like glutamine. Research suggests that SLC43A3 may play a role in cancer progression, as dysregulation of amino acid transport can impact cell growth and metabolism.
By targeting the SLC43A3 protein with this antibody, researchers can gain insights into its function and potential therapeutic implications in diseases like cancer.With its specificity for SLC43A3, this antibody is a valuable tool for studies in cancer biology, metabolism, and amino acid transport mechanisms. By enabling the detection and analysis of SLC43A3 in various cell types, this antibody facilitates research into the mechanisms underlying amino acid transport and its impact on cellular function.
Immunofluorescent analysis of MCF-7 cells using PACO39950 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human lung tissue using PACO39950 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human heart tissue using PACO39950 at dilution of 1:100.
Background:
Putative transporter.
Synonyms:
Solute carrier family 43 member 3 (Protein FOAP-13), SLC43A3
UniProt Protein Function:
SLC43A3: Putative transporter. Belongs to the SLC43A transporter (TC 2.A.1.44) family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 11q11Cellular Component: integral to membraneBiological Process: transmembrane transport