The SLC43A1 Polyclonal Antibody (PACO12296) is a valuable tool for researchers studying SLC43A1, a member of the solute carrier family of proteins involved in the transport of various molecules across cell membranes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.SLC43A1 is known to play a role in the transport of amino acids, particularly leucine, and its dysregulation has been linked to various metabolic disorders and diseases.
The SLC43A1 Polyclonal Antibody binds specifically to the SLC43A1 protein, enabling precise detection and analysis in a variety of cell types.Research into SLC43A1 is essential for understanding its function in cellular metabolism and nutrient uptake, and its potential implications in diseases related to amino acid transport. This antibody is a valuable tool for studies focusing on metabolism, cancer biology, and related fields, providing insights into the role of SLC43A1 in health and disease.
Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.
NCBI Summary:
SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008]
