The SLC40A1 Polyclonal Antibody (CAB14885) is specifically designed for research involving SLC40A1, a key protein involved in iron transport and homeostasis. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the SLC40A1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal tool for studies in areas such as metabolism, iron regulation, and hematologic disorders.
SLC40A1, also known as ferroportin, is a crucial transmembrane protein responsible for exporting iron from cells into the bloodstream. Its role in regulating systemic iron levels makes it a target of interest in research on conditions such as anemia, hemochromatosis, and iron-overload disorders. Understanding the function and regulation of SLC40A1 is essential for developing therapies aimed at modulating iron metabolism and addressing related diseases.
Product Name:
SLC40A1 Polyclonal Antibody
SKU:
CAB14885
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-270 of human SLC40A1 (NP_055400.1).
The protein encoded by this gene is a cell membrane protein that may be involved in iron export from duodenal epithelial cells. Defects in this gene are a cause of hemochromatosis type 4 (HFE4).
Purification Method:
Affinity purification
Gene ID:
30061
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC40A1 Rabbit pAb (CAB14885) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
