The SLC3A2 Polyclonal Antibody (CAB5702) is a valuable tool for researchers studying SLC3A2, a cell surface protein known for its role in amino acid transport and cellular metabolism. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the SLC3A2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential reagent for studies in metabolism, transport biology, and cancer research.
SLC3A2, also known as CD98, plays a crucial role in nutrient uptake and cellular signaling, making it a key player in processes like protein synthesis and cell growth. Its involvement in amino acid transport makes it a promising target for research on metabolic disorders, cancer metabolism, and drug resistance mechanisms. By understanding the function of SLC3A2, researchers can uncover new insights into cellular metabolism and develop novel therapies targeting nutrient uptake in various disease contexts.
Product Name:
CD98 Rabbit Polyclonal Antibody
SKU:
CAB5702
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 206-630 of human SLC3A2/CD98hc (NP_002385.3).
Apical cell membrane, Melanosome, Single-pass type II membrane protein.
Calculated MW:
58kDa
Observed MW:
75-120kDa/70-130kDa
This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
6520
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC3A2/CD98hc Rabbit pAb (CAB5702) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
