The SLC39A6 Polyclonal Antibody (CAB4584) is a valuable tool for researchers studying the SLC39A6 protein, a critical transporter involved in cellular zinc uptake and homeostasis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By binding specifically to the SLC39A6 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential resource for studies in molecular biology, biochemistry, and metal ion transport.
SLC39A6, also known as Zip6, plays a vital role in maintaining zinc balance within cells, which is essential for numerous cellular processes such as DNA synthesis, cell proliferation, and immune function. Dysregulation of SLC39A6 has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic conditions. By investigating the function of SLC39A6, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.
Product Name:
SLC39A6 Rabbit Polyclonal Antibody
SKU:
CAB4584
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-320 of human SLC39A6 (NP_001092876.1).
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).
Purification Method:
Affinity purification
Gene ID:
25800
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SLC39A6 antibody (CAB4584) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
