The SLC39A4 Polyclonal Antibody (CAB3454) is a valuable tool for researchers studying the SLC39A4 protein, also known as ZIP4, which plays a critical role in cellular zinc homeostasis. This antibody, generated in rabbits, specifically targets the SLC39A4 protein and is highly reactive with human samples.SLC39A4 is a zinc transporter that regulates the cellular uptake of zinc, an essential micronutrient involved in numerous physiological processes. Dysregulation of zinc homeostasis has been associated with various diseases, including cancer, neurodegenerative disorders, and metabolic conditions.
By detecting and analyzing SLC39A4 expression in different cell types, this antibody can aid in understanding the role of zinc in cellular function and disease pathogenesis.Validated for use in Western blot applications, the SLC39A4 Polyclonal Antibody enables researchers to investigate the expression and localization of the SLC39A4 protein in various experimental settings. Its versatility makes it a valuable tool for studies in zinc biology, metabolism, and disease mechanisms.
Product Name:
SLC39A4 Rabbit Polyclonal Antibody
SKU:
CAB3454
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-327 of human SLC39A4 (NP_570901.2).
This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
55630
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and 293T cells transfected with SLC39A4 using SLC39A4 Rabbit pAb (CAB3454) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
