ZIP14 Rabbit Polyclonal Antibody (CAB10413)
- SKU:
- CAB10413
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | ZIP14 Rabbit Polyclonal Antibody |
SKU: | CAB10413 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 101-200 of human ZIP14 (NP_001121903.1). |
Sequence: | HNFS EQSR IGSS ELQE FCPT ILQQ LDSR ACTS ENQE NEEN EQTE EGRP SAVE VWGY GLLC VTVI SLCS LLGA SVVP FMKK TFYK RLLL YFIA LAIG TLYS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | HCIN; NET34; ZIP14; cig19; HMNDYT2; LZT-Hs4 |
Positive Sample: | Mouse heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cell projection, Multi-pass membrane protein, lamellipodium. |
Calculated MW: | 54kDa |
Observed MW: | 54kDa |
This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia.
Purification Method: | Affinity purification |
Gene ID: | 23516 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |