The SLC39A11 Polyclonal Antibody (PAC039902) is a valuable tool for researchers studying the SLC39A11 protein, a member of the SLC39 family of zinc transporters. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SLC39A11 protein, this antibody allows for the detection and analysis of SLC39A11 expression in various cell types, making it an ideal choice for studies in molecular biology and zinc metabolism research.
SLC39A11 plays a crucial role in regulating zinc homeostasis within cells, impacting various biological processes such as cell proliferation, immune response, and DNA repair. Dysregulation of SLC39A11 has been linked to diseases like cancer, neurodegenerative disorders, and diabetes, making it an important target for therapeutic interventions. Gaining a deeper understanding of SLC39A11 function is essential for developing targeted treatments to combat these diseases and improve human health.
Antibody Name:
SLC39A11 Antibody (PACO39902)
Antibody SKU:
PACO39902
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Zinc transporter ZIP11 protein (93-193AA)
Immunofluorescent analysis of MCF-7 cells using PACO39902 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Functions as a cellular zinc transporter.
Synonyms:
Zinc transporter ZIP11 (Solute carrier family 39 member 11) (Zrt- and Irt-like protein 11) (ZIP-11), SLC39A11, C17orf26 ZIP11
UniProt Protein Function:
SLC39A11: May act as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Transporter; Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-passChromosomal Location of Human Ortholog: 17q24.3-q25.1Cellular Component: integral to membraneMolecular Function: metal ion transmembrane transporter activityBiological Process: zinc ion transport; transmembrane transport
