The SLC38A6 Polyclonal Antibody (PAC037902) is a valuable tool for researchers studying the SLC38A6 protein, a member of the solute carrier family involved in amino acid transport. Raised in rabbits, this antibody is highly specific to human samples and is validated for use in Western blot applications. By binding to the SLC38A6 protein, researchers can easily detect and analyze its expression in various cell types, making it ideal for studies in metabolism and cancer research.
SLC38A6 plays a crucial role in amino acid transport across cellular membranes, impacting various biological processes such as protein synthesis, cell growth, and nutrient sensing. Dysregulation of SLC38A6 has been linked to metabolic disorders and cancer progression, making it a promising target for therapeutic interventions. Understanding the function of SLC38A6 is essential for developing treatments that target amino acid metabolism in disease states.
Western blot. All lanes: SLC38A6 antibody at 12µg/ml. Lane 1: Mouse kidney tissue. Lane 2: Mouse thymus tissue. Lane 3: U87 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 51, 58 kDa. Observed band size: 51, 33 kDa.
Immunofluorescent analysis of A431 cells using PACO37902 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Probable sodium-dependent amino acid, proton antiporter, could be a neuronal transporter for glutamate.
SLC38A6: Probable sodium-dependent amino acid/proton antiporter. Belongs to the amino acid/polyamine transporter 2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 14q23.1Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: amino acid transmembrane transporter activityBiological Process: sodium ion transport
