UniProt Protein Function: | SLC38A2: Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood- brain barrier and in the supply of maternal nutrients to the fetus through the placenta. Belongs to the amino acid/polyamine transporter 2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integralChromosomal Location of Human Ortholog: 12qCellular Component: axon; brush border; cell soma; dendrite; integral to plasma membrane; plasma membrane; sarcolemmaMolecular Function: amino acid transmembrane transporter activity; protein binding; symporter activityBiological Process: alanine transport; amino acid transport; cellular response to amino acid starvation; cerebral cortex development; female pregnancy; glutamate secretion; glycine betaine transport; ion transport; neurotransmitter secretion; sodium ion transport; synaptic transmission; transmembrane transport |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q96QD8 |
NCBI GenInfo Identifier: | 162416227 |
NCBI Gene ID: | 54407 |
NCBI Accession: | Q96QD8.2 |
UniProt Secondary Accession: | Q96QD8,Q6IA88, Q6ZMG2, Q9HAV3, Q9NVA8, Q9P2G5 |
UniProt Related Accession: | Q96QD8 |
Molecular Weight: | |
NCBI Full Name: | Sodium-coupled neutral amino acid transporter 2 |
NCBI Synonym Full Names: | solute carrier family 38 member 2 |
NCBI Official Symbol: | SLC38A2Â Â |
NCBI Official Synonym Symbols: | ATA2; SAT2; SNAT2; PRO1068Â Â |
NCBI Protein Information: | sodium-coupled neutral amino acid transporter 2 |
UniProt Protein Name: | Sodium-coupled neutral amino acid transporter 2 |
UniProt Synonym Protein Names: | Amino acid transporter A2; Protein 40-9-1; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino acid transporter 2 |
Protein Family: | Sodium-coupled neutral amino acid transporter |
UniProt Gene Name: | SLC38A2Â Â |
UniProt Entry Name: | S38A2_HUMAN |