The SLC38A2 Polyclonal Antibody (PACO4638) is a powerful tool for studying SLC38A2, a key transporter protein involved in amino acid uptake and cellular metabolism. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, and has been validated for use in Western blot applications.SLC38A2, also known as sodium-coupled neutral amino acid transporter 2, plays a crucial role in the regulation of amino acid homeostasis and nutrient sensing in cells. Dysregulation of SLC38A2 has been associated with various diseases, including cancer and metabolic disorders, making it an attractive target for research in these areas.
By using the SLC38A2 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of SLC38A2 in different cell types and physiological conditions. This antibody is a valuable tool for studies in cell biology, metabolism, and disease mechanisms, providing a deeper understanding of the role of SLC38A2 in health and disease.
Antibody Name:
SLC38A2 Antibody
Antibody SKU:
PACO04638
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human SNAT2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
SLC38A2; ATA2; KIAA1382; SAT2; SNAT2; Sodium-coupled neutral amino acid transporter 2; Amino acid transporter A2; Protein 40-9-1; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino a
UniProt Protein Function:
SLC38A2: Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood- brain barrier and in the supply of maternal nutrients to the fetus through the placenta. Belongs to the amino acid/polyamine transporter 2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integralChromosomal Location of Human Ortholog: 12qCellular Component: axon; brush border; cell soma; dendrite; integral to plasma membrane; plasma membrane; sarcolemmaMolecular Function: amino acid transmembrane transporter activity; protein binding; symporter activityBiological Process: alanine transport; amino acid transport; cellular response to amino acid starvation; cerebral cortex development; female pregnancy; glutamate secretion; glycine betaine transport; ion transport; neurotransmitter secretion; sodium ion transport; synaptic transmission; transmembrane transport
Amino acid transporter A2; Protein 40-9-1; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino acid transporter 2
