The SLC37A4 Polyclonal Antibody (CAB14564) is a valuable tool for researchers studying SLC37A4, a transmembrane protein involved in glucose-6-phosphate transport. This antibody, generated in rabbits, demonstrates high specificity and sensitivity for human samples, making it ideal for use in Western blot applications. By targeting the SLC37A4 protein, researchers can accurately detect and analyze its expression in various cell types, facilitating studies in metabolism, glycogen storage diseases, and glucose homeostasis.SLC37A4, also known as the glucose-6-phosphate translocase, plays a crucial role in glucose metabolism by facilitating the transport of glucose-6-phosphate into the lumen of the endoplasmic reticulum.
Dysregulation of SLC37A4 function is associated with glycogen storage diseases and metabolic disorders, highlighting its importance in maintaining proper glucose levels in the body. Research on SLC37A4 can provide insights into the pathogenesis of these diseases and aid in the development of targeted therapeutic interventions aimed at restoring glucose homeostasis.
Product Name:
SLC37A4 Rabbit Polyclonal Antibody
SKU:
CAB14564
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 330-429 of human SLC37A4 (NP_001458.1).
This gene regulates glucose-6-phosphate transport from the cytoplasm to the lumen of the endoplasmic reticulum, in order to maintain glucose homeostasis. It also plays a role in ATP-mediated calcium sequestration in the lumen of the endoplasmic reticulum. Mutations in this gene have been associated with various forms of glycogen storage disease. Alternative splicing in this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2542
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HepG2 cells, using SLC37A4 Rabbit pAb (CAB14564) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
