SLC35B1 Antibody (PACO29956)
- SKU:
- PACO29956
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
SLC35B1 Antibody (PACO29956)
The SLC35B1 Polyclonal Antibody (PAC029956) is a valuable tool for research involving SLC35B1, a member of the SLC35 family of nucleotide sugar transporters that play a crucial role in glycosylation processes. This antibody, generated in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the SLC35B1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it well-suited for studies in glycobiology and metabolic disorders.SLC35B1 is essential for the transport of nucleotide sugars across cellular membranes, facilitating the biosynthesis of glycoproteins and glycolipids that are vital for various physiological processes.
Dysregulation of SLC35B1 has been implicated in disorders such as congenital disorders of glycosylation and cancer, highlighting its potential as a therapeutic target. Investigating the function of SLC35B1 can provide valuable insights into the mechanisms of glycosylation-related diseases and aid in the development of targeted interventions to correct aberrant glycosylation patterns.
| Antibody Name: | SLC35B1 Antibody (PACO29956) |
| Antibody SKU: | PACO29956 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Solute carrier family 35 member B1 protein (106-135AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: SLC35B1 antibody at 4µg/ml + HL60 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 36, 40 kDa Observed band size: 36 kDa . |
 | Immunofluorescent analysis of HepG2 cells using PACO29956 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Probable sugar transporter. |
| Synonyms: | Solute carrier family 35 member B1 (UDP-galactose transporter-related protein 1) (UGTrel1) (hUGTrel1), SLC35B1, UGTREL1 |
| UniProt Protein Function: | SLC35B1: Probable sugar transporter. Belongs to the nucleotide-sugar transporter family. SLC35B subfamilyProtein type: Membrane protein, integral; Transporter; Transporter, SLC family; Membrane protein, multi-passChromosomal Location of Human Ortholog: 17q21.33Cellular Component: endoplasmic reticulum membrane; integral to membrane; intracellular membrane-bound organelleMolecular Function: UDP-galactose transmembrane transporter activityBiological Process: transport |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a nucleotide sugar transporter which is a member of solute carrier family 35. The transporters in this family are highly conserved hydrophobic proteins with multiple transmembrane domains. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] |
| UniProt Code: | P78383 |
| NCBI GenInfo Identifier: | 523704333 |
| NCBI Gene ID: | 10237 |
| NCBI Accession: | NP_005818.2 |
| UniProt Secondary Accession: | P78383,Q96EW7, B4DEC4, J3KQV4 |
| UniProt Related Accession: | P78383 |
| Molecular Weight: | 39,512 Da |
| NCBI Full Name: | solute carrier family 35 member B1 isoform 1 |
| NCBI Synonym Full Names: | solute carrier family 35 member B1 |
| NCBI Official Symbol: | SLC35B1Â Â |
| NCBI Official Synonym Symbols: | UGTREL1Â Â |
| NCBI Protein Information: | solute carrier family 35 member B1 |
| UniProt Protein Name: | Solute carrier family 35 member B1 |
| UniProt Synonym Protein Names: | UDP-galactose transporter-related protein 1; UGTrel1; hUGTrel1 |
| Protein Family: | Solute carrier family |
| UniProt Gene Name: | SLC35B1Â Â |
| UniProt Entry Name: | S35B1_HUMAN |
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