The SLC35A1 Polyclonal Antibody is a valuable tool for researchers studying SLC35A1, a key protein involved in nucleotide sugar transport. This rabbit-derived antibody is highly specific and reactive with human samples, making it ideal for Western blot applications. By binding to the SLC35A1 protein, researchers can detect and analyze its expression in various cell types, aiding in studies related to glycosylation processes and metabolic disorders.SLC35A1 plays a crucial role in the transport of nucleotide sugars across cell membranes, which is essential for glycosylation and proper functioning of glycoproteins.
Dysregulation of SLC35A1 has been linked to various metabolic disorders and diseases, highlighting its importance in cellular processes. By using the SLC35A1 Polyclonal Antibody, researchers can further understand the role of this protein in health and disease, with potential implications for drug development and therapeutic interventions.
Product Name:
SLC35A1 Polyclonal Antibody
SKU:
CAB10658
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SLC35A1 (NP_006407.1).
The protein encoded by this gene is found in the membrane of the Golgi apparatus, where it transports nucleotide sugars into the Golgi. One such nucleotide sugar is CMP-sialic acid, which is imported into the Golgi by the encoded protein and subsequently glycosylated. Defects in this gene are a cause of congenital disorder of glycosylation type 2F (CDG2F). Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10559
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC35A1 Rabbit pAb (CAB10658) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
