The SLC34A1 Polyclonal Antibody (CAB6742) is a valuable tool for researchers studying SLC34A1, a protein involved in phosphate transport and homeostasis. The antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SLC34A1 protein, this antibody enables accurate detection and analysis in various cell types, making it an ideal choice for studies in physiology, biochemistry, and nephrology.SLC34A1, also known as the type II sodium-dependent phosphate transporter, plays a crucial role in maintaining phosphate balance in the body.
Dysregulation of phosphate transport has been linked to various disorders such as hypophosphatemia and kidney diseases. By investigating the function and expression of SLC34A1, researchers can gain insights into the mechanisms underlying these conditions and potentially identify therapeutic targets for their treatment.Overall, the SLC34A1 Polyclonal Antibody offers a reliable and specific tool for the study of SLC34A1 in various research areas, providing valuable information that could advance our understanding of phosphate homeostasis and related diseases.
Product Name:
SLC34A1 Polyclonal Antibody
SKU:
CAB6742
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 562-639 of human SLC34A1 (NP_003043.3).
Enables sodium:phosphate symporter activity. Involved in several processes, including phosphate ion homeostasis; phosphate ion transport; and response to lead ion. Located in several cellular components, including apical plasma membrane; mitotic spindle; and nuclear speck. Implicated in several diseases, including Fanconi syndrome (multiple); chronic kidney disease; hereditary hypophosphatemic rickets with hypercalciuria; hypophosphatemic nephrolithiasis/osteoporosis 1; and nephrolithiasis.
Purification Method:
Affinity purification
Gene ID:
6569
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC34A1 Rabbit pAb (CAB6742) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
