The SLC34A1 Polyclonal Antibody (CAB13635) is a cutting-edge research tool designed for studying SLC34A1, a critical cell surface transporter involved in the regulation of phosphate homeostasis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in Western blot applications. By binding to the SLC34A1 protein, researchers can accurately detect and analyze its expression in various cell types, offering a valuable tool for investigations in the fields of biochemistry, physiology, and disease pathology.SLC34A1, also known as sodium-dependent phosphate transporter 2A, plays a vital role in the transport of phosphate ions across cell membranes, crucial for maintaining proper mineral balance in the body.
Dysregulation of SLC34A1 function has been implicated in various disorders, including osteoporosis, renal calculi formation, and hypophosphatemic rickets. Investigating the mechanisms underlying SLC34A1 activity is essential for developing targeted therapies aimed at restoring phosphate homeostasis and treating related conditions.Whether exploring the physiological functions of SLC34A1 or investigating its role in disease pathology, the SLC34A1 Polyclonal Antibody (CAB13635) offers researchers a reliable and specific tool for precise detection and analysis of this important transporter protein. Unlock the potential of SLC34A1 research with this high-quality antibody, advancing our understanding of phosphate metabolism and
Product Name:
SLC34A1 Rabbit Polyclonal Antibody
SKU:
CAB13635
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 562-639 of human SLC34A1 (NP_003043.3).
Enables sodium:phosphate symporter activity. Involved in several processes, including phosphate ion homeostasis; phosphate ion transport; and response to lead ion. Located in several cellular components, including apical plasma membrane; mitotic spindle; and nuclear speck. Implicated in several diseases, including Fanconi syndrome (multiple); chronic kidney disease; hereditary hypophosphatemic rickets with hypercalciuria; hypophosphatemic nephrolithiasis/osteoporosis 1; and nephrolithiasis.
Purification Method:
Affinity purification
Gene ID:
6569
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC34A1 Rabbit pAb (CAB13635) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
