The SLC31A2 Polyclonal Antibody (CAB16362) is specifically designed for research involving the SLC31A2 protein, a key player in copper transport and regulation within the body. This antibody, produced using rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SLC31A2 protein, researchers can effectively detect and analyze its expression in various cell types, making it an essential tool for studies in the fields of biochemistry, molecular biology, and disease research.
SLC31A2, also known as the copper transporter 1 (CTR1), plays a crucial role in maintaining copper homeostasis and facilitating copper uptake into cells. Dysregulation of SLC31A2 has been linked to copper-related disorders such as Menkes disease and Wilson's disease, as well as certain types of cancer where copper metabolism is dysregulated. Understanding the function and regulation of SLC31A2 is vital for developing targeted therapies for these diseases and advancing our knowledge of copper metabolism in health and disease.
Product Name:
Slc31a2 Rabbit Polyclonal Antibody
SKU:
CAB16362
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of mouse Slc31a2 (NP_001277447.1).
Acts upstream of or within cellular copper ion homeostasis and regulation of copper ion transmembrane transport. Located in late endosome; membrane; and recycling endosome. Is expressed in brain; retina nuclear layer; and urinary system. Orthologous to human SLC31A2 (solute carrier family 31 member 2).
Purification Method:
Affinity purification
Gene ID:
20530
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse pancreas, using Slc31a2 Rabbit pAb (CAB16362) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
