The SLC31A1 Polyclonal Antibody (CAB10109) is a valuable tool for researchers studying SLC31A1, a key protein involved in copper transport and homeostasis in cells. This antibody, produced using rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the SLC31A1 protein, researchers can effectively detect and analyze its presence in various cell types, making it an essential component of studies in the fields of biochemistry and cell biology.
SLC31A1, also known as the copper transporter 1, plays a crucial role in maintaining copper levels within cells and supporting various cellular functions, including enzyme activity and mitochondrial function. Dysregulation of SLC31A1 has been linked to copper metabolism disorders and diseases such as Wilson disease. Understanding the function and regulation of SLC31A1 is essential for developing targeted therapies for copper-related disorders and advancing our knowledge of cellular copper homeostasis.
Product Name:
SLC31A1 Rabbit Polyclonal Antibody
SKU:
CAB10109
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human SLC31A1 (NP_001850.1).
The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper.
Purification Method:
Affinity purification
Gene ID:
1317
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SLC31A1 antibody (CAB10109) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
