The SLC30A9 Polyclonal Antibody (PACO22738) is a valuable tool for researchers studying SLC30A9, a member of the SLC30 zinc transporter family known to play a role in zinc homeostasis and cellular zinc efflux. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to the SLC30A9 protein, this antibody enables precise detection and analysis in various cell types, making it an ideal choice for studies in metabolism, cellular signaling, and neurobiology.
SLC30A9 is a crucial player in cellular zinc transport and homeostasis, which is essential for a wide range of biological processes including immune function, neuronal development, and insulin secretion. Dysregulation of zinc transporters like SLC30A9 has been implicated in various diseases such as diabetes, Alzheimer's, and cancer, making it a promising target for therapeutic interventions. Understanding the functions and regulation of SLC30A9 is key to unlocking its potential in the development of novel treatments for these conditions.
Antibody Name:
SLC30A9 Antibody (PACO22738)
Antibody SKU:
PACO22738
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human SLC30A9.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HuvEC cells, using SLC30A9 antibody.
Background:
Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt-responsive genes.
Synonyms:
Zinc transporter 9; ZnT-9; Solute carrier family 30 member 9; Human embryonic lung protein; HUEL
UniProt Protein Function:
SLC30A9: Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors. Plays a role in transcriptional activation of Wnt- responsive genes. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.Protein type: Nuclear receptor co-regulator; Membrane protein, multi-pass; Transporter; Transporter, SLC family; Motility/polarity/chemotaxis; Cytoskeletal; Membrane protein, integralChromosomal Location of Human Ortholog: 4p13Cellular Component: cytoskeleton; integral to membrane; nucleusMolecular Function: ligand-dependent nuclear receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; cation transmembrane transporter activity; chromatin binding; transcription factor activityBiological Process: transcription, DNA-dependent; nucleotide-excision repair; positive regulation of transcription from RNA polymerase II promoter; zinc ion transport
solute carrier family 30 (zinc transporter), member 9
NCBI Official Symbol:
SLC30A9Â Â
NCBI Official Synonym Symbols:
HUEL; ZNT9; GAC63; C4orf1Â Â
NCBI Protein Information:
zinc transporter 9; znT-9; human embryonic lung protein; expressed in human embryonic lung; solute carrier family 30 member 9; GRIP1-dependent nuclear receptor coactivator
UniProt Protein Name:
Zinc transporter 9
UniProt Synonym Protein Names:
Human embryonic lung protein; HuEL; Solute carrier family 30 member 9
