The SLC30A1 Polyclonal Antibody (CAB12532) is a valuable tool for researchers studying SLC30A1, a protein involved in zinc transport and homeostasis within cells. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SLC30A1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigation in fields such as biochemistry and cellular biology.
SLC30A1, also known as ZnT-1, plays a crucial role in maintaining zinc balance within cells by facilitating the efflux of zinc ions out of the cytoplasm. Dysregulation of zinc homeostasis has been implicated in various diseases, including diabetes, Alzheimer's, and cancer. Research into the function of SLC30A1 is essential for understanding the mechanisms underlying these conditions and may lead to the development of novel therapeutic strategies targeting zinc transport pathways.
Product Name:
SLC30A1 Rabbit Polyclonal Antibody
SKU:
CAB12532
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 251-350 of human SLC30A1 (NP_067017.2).
Predicted to enable calcium channel inhibitor activity and zinc ion transmembrane transporter activity. Predicted to be involved in several processes, including cellular divalent inorganic cation homeostasis; inorganic cation transmembrane transport; and negative regulation of transport. Predicted to act upstream of or within in utero embryonic development. Located in several cellular components, including Golgi apparatus; endoplasmic reticulum; and nuclear membrane.
Purification Method:
Affinity purification
Gene ID:
7779
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC30A1 Rabbit pAb (CAB12532) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
