The SLC2A9 Polyclonal Antibody (CAB14606) is a valuable tool for researchers studying SLC2A9, a transporter protein involved in urate homeostasis and gout development. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in Western blot applications. By binding to the SLC2A9 protein, this antibody allows for easy detection and analysis in various cell types, making it an ideal choice for studies in metabolic disorders and kidney disease.SLC2A9, also known as GLUT9, plays a crucial role in regulating urate levels in the body by facilitating urate reabsorption in the kidneys. Dysregulation of SLC2A9 function has been implicated in gout, a painful inflammatory arthritis caused by the build-up of uric acid crystals.
Research into the mechanisms underlying SLC2A9 activity is essential for developing targeted therapies for gout and other disorders related to urate metabolism.By utilizing the SLC2A9 Polyclonal Antibody, researchers can gain valuable insights into the function of this transporter protein and its role in maintaining urate homeostasis. This antibody is a valuable asset for investigations into gout pathogenesis, as well as for identifying potential therapeutic targets for the treatment of metabolic disorders involving aberrant uric acid metabolism.
Product Name:
SLC2A9 Rabbit Polyclonal Antibody
SKU:
CAB14606
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 429-529 of human SLC2A9 (NP_064425.2).
This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
56606
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC2A9 Rabbit pAb (CAB14606) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
