The SLC2A8 Polyclonal Antibody (CAB16521) is a vital tool for research involving SLC2A8, a glucose transporter protein that plays a crucial role in glucose homeostasis and insulin sensitivity. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SLC2A8 protein, this antibody enables accurate detection and analysis in various cell types, making it perfect for studies in metabolic disorders and diabetes research.
SLC2A8, also known as GLUT8, is involved in the transport of glucose across cell membranes and is particularly important in tissues such as the liver, adipose tissue, and muscle. Dysregulation of SLC2A8 function has been linked to insulin resistance and metabolic syndrome, making it a promising target for therapeutic interventions in diabetes and related metabolic diseases. Understanding the role of SLC2A8 in glucose metabolism is essential for developing new strategies to manage these conditions effectively.
Product Name:
SLC2A8 Rabbit Polyclonal Antibody
SKU:
CAB16521
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-260 of human SLC2A8 (NP_055395.2).
This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
29988
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC2A8 Rabbit pAb (CAB16521) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
