The SLC2A1 Polyclonal Antibody (CAB6982) is a valuable tool for researchers studying SLC2A1, a key protein involved in glucose transport across cell membranes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the SLC2A1 protein, researchers can accurately detect and analyze its expression levels in various cell types, providing insights into glucose metabolism and its implications in diseases such as cancer, diabetes, and metabolic disorders.
SLC2A1, also known as glucose transporter 1 (GLUT1), plays a crucial role in maintaining glucose homeostasis by facilitating the transport of glucose into cells. Dysregulation of SLC2A1 has been implicated in various pathological conditions, highlighting its importance as a potential therapeutic target. This antibody enables researchers to explore the function and regulation of SLC2A1, advancing our understanding of glucose metabolism and its impact on human health.
Product Name:
GLUT1/SLC2A1 Rabbit Polyclonal Antibody
SKU:
CAB6982
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 210-310 of human GLUT1/SLC2A1 (NP_006507.2).
This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia.
Purification Method:
Affinity purification
Gene ID:
6513
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using GLUT1/SLC2A1 Rabbit pAb (CAB6982) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
