The SLC2A1 Polyclonal Antibody (CAB11208) is a valuable tool for researchers studying SLC2A1, a key protein involved in glucose transport across cell membranes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SLC2A1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in metabolism, diabetes, and cancer research.SLC2A1, also known as glucose transporter 1 (GLUT1), plays a crucial role in maintaining glucose homeostasis in the body.
Dysregulation of SLC2A1 has been implicated in various diseases, including diabetes and cancer, highlighting the importance of studying its function and regulation. By utilizing the SLC2A1 Polyclonal Antibody, researchers can gain insights into the role of SLC2A1 in cellular metabolism and disease pathogenesis, paving the way for potential therapeutic interventions targeting glucose transport pathways.
Product Name:
GLUT1/SLC2A1 Rabbit Polyclonal Antibody
SKU:
CAB11208
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-400 of human GLUT1/SLC2A1 (NP_006507.2).
This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia.
Purification Method:
Affinity purification
Gene ID:
6513
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HepG2 cells, using GLUT1/SLC2A1 Rabbit pAb (CAB11208) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
