The SLC27A2 Polyclonal Antibody (CAB1077) is a valuable tool for research involving SLC27A2, a protein involved in fatty acid metabolism and lipid droplet formation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SLC27A2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in metabolism, obesity, and lipid-related disorders.SLC27A2, also known as FATP2 (fatty acid transport protein 2), plays a crucial role in the uptake and transport of long-chain fatty acids into cells, contributing to energy storage and lipid metabolism.
Dysregulation of SLC27A2 has been implicated in metabolic disorders such as obesity, diabetes, and fatty liver disease, highlighting its importance in maintaining metabolic balance. Further research into the function of SLC27A2 may provide valuable insights for developing targeted therapies for these conditions.Overall, the SLC27A2 Polyclonal Antibody (CAB1077) is an essential tool for scientists studying the role of SLC27A2 in lipid metabolism and its implications for metabolic diseases. Its high specificity and reactivity make it a reliable choice for researchers investigating the intricate mechanisms underlying fatty acid transport and cellular lipid homeostasis.
Product Name:
SLC27A2 Rabbit Polyclonal Antibody
SKU:
CAB1077
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 290-573 of human FATP2 (NP_003636.2).
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
11001
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC27A2 Rabbit pAb (CAB1077) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
