SLC26A8 Antibody (PACO39890)
- SKU:
- PACO39890
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SLC26A8 Antibody (PACO39890) |
Antibody SKU: | PACO39890 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Testis anion transporter 1 protein (414-595AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO39890 at dilution of 1:100. |
![]() | Immunofluorescent analysis of HepG2 cells using PACO39890 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO39890 at dilution of 1:100. |
Background: | Acts as a DIDS-sensitive anion exchanger mediating chloride, sulfate and oxalate transport. May fulfill critical anion exchange functions in male germ line during meiosis and hence may play a role in spermatogenesis. May be involved in a new regulatory pathway linking sulfate transport to RhoGTPase signaling in male germ cells. A critical component of the sperm annulus that is essential for correct sperm tail differentiation and motility and hence male fertility. May form a moleculer complex involved in the regulation of chloride and bicarbonate ions fluxes during sperm capacitation. |
Synonyms: | Testis anion transporter 1 (Anion exchange transporter) (Solute carrier family 26 member 8), SLC26A8, TAT1 |
UniProt Protein Function: | Acts as a DIDS-sensitive anion exchanger mediating chloride, sulfate and oxalate transport. May fulfill critical anion exchange functions in male germ line during meiosis and hence may play a role in spermatogenesis. May be involved in a new regulatory pathway linking sulfate transport to RhoGTPase signaling in male germ cells. A critical component of the sperm annulus that is essential for correct sperm tail differentiation and motility and hence male fertility. May form a moleculer complex involved in the regulation of chloride and bicarbonate ions fluxes during sperm capacitation. |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the SLC26 gene family of anion transporters. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. The expression of this gene appears to be restricted to spermatocytes. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2010] |
UniProt Code: | Q96RN1 |
NCBI GenInfo Identifier: | 16418457 |
NCBI Gene ID: | 116369 |
NCBI Accession: | NP_443193.1 |
UniProt Secondary Accession: | Q96RN1,Q5JVR5, Q812C7, Q8TC65, Q96MA0, Q96PK8 |
UniProt Related Accession: | Q96RN1 |
Molecular Weight: | 85,680 Da |
NCBI Full Name: | testis anion transporter 1 isoform a |
NCBI Synonym Full Names: | solute carrier family 26 member 8 |
NCBI Official Symbol: | SLC26A8Â Â |
NCBI Official Synonym Symbols: | TAT1; SPGF3Â Â |
NCBI Protein Information: | testis anion transporter 1 |
UniProt Protein Name: | Testis anion transporter 1 |
UniProt Synonym Protein Names: | Anion exchange transporter; Solute carrier family 26 member 8 |
Protein Family: | Valine/tyrosine/tryptophan amino-acid permease |
UniProt Gene Name: | SLC26A8Â Â |
UniProt Entry Name: |