The SLC25A6 Polyclonal Antibody (CAB3585) is a versatile research tool designed for studying the SLC25A6 protein, also known as the adenine nucleotide translocator 3 (ANT3). This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the SLC25A6 protein, this antibody allows for the detection and analysis of SLC25A6 in various cell types, making it an essential tool for research in the fields of bioenergetics, mitochondrial function, and metabolism.SLC25A6 is a mitochondrial transporter protein that plays a crucial role in cellular energy metabolism by facilitating the exchange of ADP and ATP across the inner mitochondrial membrane.
Dysregulation of SLC25A6 has been implicated in various diseases, including metabolic disorders, neurodegenerative diseases, and cancer. Therefore, studying the expression and function of SLC25A6 is essential for understanding the molecular mechanisms underlying these pathologies and identifying potential therapeutic targets.The SLC25A6 Polyclonal Antibody (CAB3585) offers researchers a reliable and sensitive tool for investigating the role of SLC25A6 in health and disease. Its high specificity and reactivity make it an ideal choice for studies in cell biology, biochemistry, and molecular biology, providing valuable insights into the physiological functions of SLC25A6 and its potential as a therapeutic
Product Name:
SLC25A6 Rabbit Polyclonal Antibody
SKU:
CAB3585
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SLC25A6 (NP_001627.2).
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.
Purification Method:
Affinity purification
Gene ID:
293
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SLC25A6 antibody (CAB3585) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
