The SLC25A5 Polyclonal Antibody (CAB15639) is a valuable tool for researchers studying the SLC25A5 protein, also known as Adenine Nucleotide Translocase 2 (ANT2). This cell membrane protein plays a key role in cellular energy metabolism by facilitating the exchange of ADP and ATP across the mitochondrial inner membrane.Raised in rabbits, this antibody exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SLC25A5 protein, researchers can detect and analyze its expression in various cell types, making it a versatile tool for studies in cellular metabolism, bioenergetics, and mitochondrial function.
The SLC25A5 protein is essential for maintaining cellular energy homeostasis and dysfunction in its activity has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes. Understanding the role of SLC25A5 in cellular energetics is crucial for developing targeted therapies that modulate mitochondrial function in these disease contexts.Overall, the SLC25A5 Polyclonal Antibody is a valuable asset for researchers aiming to unravel the complexities of cellular energy metabolism and its impact on human health.
Product Name:
SLC25A5 Rabbit Polyclonal Antibody
SKU:
CAB15639
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 151-250 of human SLC25A5 (NP_001143.2).
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.
Purification Method:
Affinity purification
Gene ID:
292
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC25A5 Rabbit pAb (CAB15639) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
