The SLC25A46 Antibody (PAC040078) is a high-quality polyclonal antibody designed for research involving SLC25A46, a solute carrier protein located in the inner mitochondrial membrane. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. SLC25A46 plays a crucial role in mitochondrial function, particularly in the transport of metabolites across the mitochondrial membrane. Dysregulation of SLC25A46 has been linked to various diseases, including metabolic disorders and neurodegenerative diseases.
By using the SLC25A46 Antibody, researchers can effectively detect and analyze the expression of SLC25A46 in different cell types, making it an essential tool for studies in mitochondrial biology and related diseases. Understanding the function of SLC25A46 is critical for developing targeted therapies for mitochondrial disorders and related conditions.
Western blot. All lanes: SLC25A46 antibody at 6µg/ml. Lane 1: Mouse brain tissue. Lane 2: Jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 47, 31, 38 kDa. Observed band size: 47 kDa.
Immunofluorescent analysis of Hela cells using PACO40078 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Synonyms:
Solute carrier family 25 member 46, SLC25A46, TB1
UniProt Protein Function:
May play a role in mitochondrial dynamics by controlling mitochondrial membrane fission.
UniProt Protein Details:
NCBI Summary:
This gene encodes a mitochondrial solute carrier protein family member. It functions in promoting mitochondrial fission, and prevents the formation of hyperfilamentous mitochondria. Mutation of this gene results in neuropathy and optic atrophy. [provided by RefSeq, Aug 2016]
