The SLC25A4 Polyclonal Antibody (CAB1882) is a valuable tool for researchers studying the SLC25A4 protein, a mitochondrial solute carrier involved in cellular energy metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SLC25A4 protein, this antibody enables detection and analysis in a variety of cell types, making it an ideal choice for research in biochemistry, cell biology, and metabolism.SLC25A4, also known as the adenine nucleotide translocator 1 (ANT1), plays a crucial role in the transport of ATP and ADP across the mitochondrial membrane, a process essential for cellular respiration and energy production.
Dysregulation of SLC25A4 has been implicated in various metabolic disorders, neurodegenerative diseases, and cancer. Therefore, studying the function and expression of SLC25A4 is key to understanding its role in health and disease, and may have important implications for the development of targeted therapies in the future.
Product Name:
SLC25A4 Rabbit Polyclonal Antibody
SKU:
CAB1882
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 101-200 of human SLC25A4/ANT1 (NP_001142.2).
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy.
Purification Method:
Affinity purification
Gene ID:
291
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SLC25A4/ANT1 antibody (CAB1882) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
