The SLC25A4 Polyclonal Antibody (CAB15027) is a valuable tool for researchers studying SLC25A4, a mitochondrial protein known for its role in cellular energy metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SLC25A4 protein, this antibody enables researchers to detect and analyze SLC25A4 expression in a variety of cell types, making it an excellent choice for studies in bioenergetics, metabolism, and mitochondrial function.SLC25A4, also known as the adenine nucleotide translocase 1 (ANT1), is a key player in the transport of ATP and ADP across the mitochondrial inner membrane, a crucial step in cellular energy production.
Dysregulation of SLC25A4 has been implicated in a variety of metabolic disorders, neurodegenerative diseases, and cancer. By gaining a better understanding of the function and regulation of SLC25A4, researchers can contribute to the development of therapeutic strategies targeting mitochondrial dysfunction and energy metabolism abnormalities in these pathological conditions.
Product Name:
SLC25A4 Rabbit Polyclonal Antibody
SKU:
CAB15027
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 40-298 of human SLC25A4/ANT1 (NP_001142.2).
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy.
Purification Method:
Affinity purification
Gene ID:
291
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC25A4/ANT1 Rabbit pAb (CAB15027) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
