The SLC25A38 Polyclonal Antibody (CAB13218) is specifically designed for research involving SLC25A38, a mitochondrial solute carrier protein involved in mitochondrial iron transport. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot and immunofluorescence applications. SLC25A38 plays a crucial role in maintaining mitochondrial iron homeostasis, which is essential for various cellular processes such as energy production and heme synthesis. Dysregulation of SLC25A38 has been implicated in conditions such as mitochondrial iron overload disorders and anemia.
Therefore, studying the expression and function of SLC25A38 using this antibody could provide valuable insights into the molecular mechanisms underlying these diseases. With its ability to detect and analyze SLC25A38 protein expression in different cell types, this antibody is a valuable tool for researchers in the fields of biochemistry, cell biology, and mitochondrial physiology. The SLC25A38 Polyclonal Antibody (CAB13218) offers a reliable and specific means to investigate the role of SLC25A38 in mitochondrial iron transport and its implications for human health.
Product Name:
SLC25A38 Rabbit Polyclonal Antibody
SKU:
CAB13218
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SLC25A38 (NP_060345.2).
This gene is a member of the mitochondrial carrier family. The encoded protein is required during erythropoiesis and is important for the biosynthesis of heme. Mutations in this gene are the cause of autosomal congenital sideroblastic anemia (anemia, sideroblastic, 2, pyridoxine-refractory). A related pseudogene is found on chromosome 1.
Purification Method:
Affinity purification
Gene ID:
54977
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of 293T cells, using SLC25A38 antibody (CAB13218) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
