The SLC25A32 Polyclonal Antibody (PAC041058) is a valuable tool for researchers studying the SLC25A32 protein, a mitochondrial carrier protein that plays a crucial role in mitochondrial function. This antibody, generated in rabbits, exhibits high sensitivity and specificity towards human samples, making it an ideal choice for Western blot applications.SLC25A32, also known as the mitochondrial pyrimidine nucleotide carrier, is involved in the transport of pyrimidine nucleotides across the inner mitochondrial membrane. This process is essential for DNA and RNA synthesis, as well as for energy production in the mitochondria.
Dysregulation of SLC25A32 has been implicated in various diseases, including metabolic disorders and cancer.By utilizing the SLC25A32 Polyclonal Antibody, researchers can study the expression and localization of SLC25A32 in different cell types and tissues, providing valuable insights into its function and potential roles in disease pathogenesis. This antibody is a valuable tool for investigations in the fields of mitochondrial biology, metabolism, and cancer research.
Antibody Name:
SLC25A32 Antibody (PACO41058)
Antibody SKU:
PACO41058
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Human, Mouse
Immunogen:
Recombinant Human Mitochondrial folate transporter/carrier protein (44-88AA)
Western Blot. Positive WB detected in: Mouse kidney tissue, Mouse skeletal muscle tissue. All lanes: SLC25A32 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 36 kDa. Observed band size: 36 kDa.
Background:
Transports folate across the inner membranes of mitochondria.
Synonyms:
Mitochondrial folate transporter/carrier (Solute carrier family 25 member 32), SLC25A32, MFT MFTC
UniProt Protein Function:
SLC25A32: Transports folate across the inner membranes of mitochondria. Belongs to the mitochondrial carrier family.Protein type: Mitochondrial; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 8q22.3Cellular Component: integral to membrane; mitochondrial inner membraneMolecular Function: folic acid transporter activity; structural constituent of ribosomeBiological Process: folic acid metabolic process; folic acid transport; glycine metabolic process; mitochondrial transport; translation; vitamin metabolic process; water-soluble vitamin metabolic process
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the P(I/L)W subfamily of mitochondrial carrier family transport proteins. The encoded protein transports folate across the inner mitochondrial membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013]
