SLC25A27 Rabbit Polyclonal Antibody (CAB13835)
- SKU:
- CAB13835
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
Product Name: | SLC25A27 Rabbit Polyclonal Antibody |
SKU: | CAB13835 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 201-300 of human SLC25A27 (NP_004268.3). |
Sequence: | ALVN MGDL TTYD TVKH YLVL NTPL EDNI MTHG LSSL CSGL VASI LGTP ADVI KSRI MNQP RDKQ GRGL LYKS STDC LIQA VQGE GFMS LYKG FLPS WLRM |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | UCP4; SLC25A27 |
Positive Sample: | mouse brain,rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion inner membrane, Multi-pass membrane protein. |
Calculated MW: | 36kDa |
Observed MW: | 36kDa |
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 9481 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |