The SLC25A27 Polyclonal Antibody (CAB13835) is a valuable tool for researchers studying SLC25A27, a key protein involved in mitochondrial function and metabolism. This antibody is produced in rabbits and is highly specific for human samples, making it a reliable choice for studies involving this protein.SLC25A27, also referred to as a mitochondrial carnitine/acylcarnitine carrier protein, is essential for the transport of fatty acids into the mitochondria for beta-oxidation. This process is crucial for energy production and maintaining cellular homeostasis.
Research on SLC25A27 is important for understanding metabolic disorders, obesity, and other diseases related to mitochondrial dysfunction.The SLC25A27 Polyclonal Antibody is validated for use in Western blot applications, allowing for precise detection and analysis of SLC25A27 protein levels in various cell types. Its specificity and reliability make it a valuable tool for investigating the role of SLC25A27 in cellular metabolism, energy production, and disease pathology.
Product Name:
SLC25A27 Rabbit Polyclonal Antibody
SKU:
CAB13835
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 201-300 of human SLC25A27 (NP_004268.3).
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9481
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC25A27 Rabbit pAb (CAB13835) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
