| UniProt Protein Function: | SLC25A25: Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria. Belongs to the mitochondrial carrier family. 6 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Transporter; Mitochondrial; Transporter, SLC family; Membrane protein, integral Chromosomal Location of Human Ortholog: 9q34.11 Cellular Component: mitochondrion; intracellular membrane-bound organelle; mitochondrial inner membrane; integral to membrane Molecular Function:calcium ion binding Biological Process: ATP metabolic process; response to food; response to dietary excess; camera-type eye development; multicellular organism growth; cellular respiration; response to activity |
| NCBI Summary: | The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene. [provided by RefSeq, Jul 2012] |
| UniProt Code: | Q6KCM7 |
| NCBI GenInfo Identifier: | 74758042 |
| NCBI Gene ID: | 114789 |
| NCBI Accession: | Q6KCM7.1 |
| UniProt Secondary Accession: | Q6KCM7,Q5SYW7, Q5SYW8, Q5SYX3, Q5VWU2, Q5VWU3, Q5VWU4 Q6KCM4, Q6KCM6, Q6UX48, Q705K2, Q96PZ1, |
| UniProt Related Accession: | Q6KCM7 |
| Molecular Weight: | 469 |
| NCBI Full Name: | Calcium-binding mitochondrial carrier protein SCaMC-2 |
| NCBI Synonym Full Names: | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 |
| NCBI Official Symbol: | SLC25A25Â Â |
| NCBI Official Synonym Symbols: | MCSC; PCSCL; SCAMC-2Â Â |
| NCBI Protein Information: | calcium-binding mitochondrial carrier protein SCaMC-2; mitochondrial ATP-Mg/Pi carrier protein 3; short calcium-binding mitochondrial carrier 2; small calcium-binding mitochondrial carrier 2; solute carrier family 25, member 25, isoform a; mitochondrial Ca(2+)-dependent solute carrier protein 3 |
| UniProt Protein Name: | Calcium-binding mitochondrial carrier protein SCaMC-2 |
| UniProt Synonym Protein Names: | Mitochondrial ATP-Mg/Pi carrier protein 3; Mitochondrial Ca(2+)-dependent solute carrier protein 3; Small calcium-binding mitochondrial carrier protein 2; Solute carrier family 25 member 25 |
| Protein Family: | Calcium-binding mitochondrial carrier protein |
| UniProt Gene Name: | SLC25A25Â Â |
| UniProt Entry Name: | SCMC2_HUMAN |
