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SLC25A25 Antibody (PACO12268)

SKU:
PACO12268
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459

Description

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SLC25A25 Antibody (PACO12268)

The SLC25A25 Antibody (PAC012268) is a valuable tool for researchers studying the SLC25A25 gene, which is involved in mitochondrial function and energy metabolism. This polyclonal antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the SLC25A25 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for research in bioenergetics, metabolism, and mitochondrial diseases.

SLC25A25, also known as mitochondrial carnitine/acylcarnitine translocase (CACT), plays a crucial role in transferring carnitine into mitochondria for fatty acid oxidation, a key process in energy production. Dysregulation of SLC25A25 has been associated with metabolic disorders, cardiovascular diseases, and neurological conditions. Studying the function of SLC25A25 is essential for understanding mitochondrial metabolism and developing targeted therapies for related disorders.

Antibody Name:SLC25A25 Antibody (PACO12268)
Antibody SKU:PACO12268
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human SLC25A25
Form:Liquid
Storage Buffer:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25;SLC25A25;KIAA1896;MCSC;MGC105138;MGC119514;MGC119515;MGC119516;MGC119517;PCSCL;RP11-395P17.4;SCAMC-2 ;
UniProt Protein Function:SLC25A25: Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria. Belongs to the mitochondrial carrier family. 6 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, multi-pass; Transporter; Mitochondrial; Transporter, SLC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q34.11

Cellular Component: mitochondrion; intracellular membrane-bound organelle; mitochondrial inner membrane; integral to membrane

Molecular Function:calcium ion binding

Biological Process: ATP metabolic process; response to food; response to dietary excess; camera-type eye development; multicellular organism growth; cellular respiration; response to activity

NCBI Summary:The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene. [provided by RefSeq, Jul 2012]
UniProt Code:Q6KCM7
NCBI GenInfo Identifier:74758042
NCBI Gene ID:114789
NCBI Accession:Q6KCM7.1
UniProt Secondary Accession:Q6KCM7,Q5SYW7, Q5SYW8, Q5SYX3, Q5VWU2, Q5VWU3, Q5VWU4 Q6KCM4, Q6KCM6, Q6UX48, Q705K2, Q96PZ1,
UniProt Related Accession:Q6KCM7
Molecular Weight:469
NCBI Full Name:Calcium-binding mitochondrial carrier protein SCaMC-2
NCBI Synonym Full Names:solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
NCBI Official Symbol:SLC25A25  
NCBI Official Synonym Symbols:MCSC; PCSCL; SCAMC-2  
NCBI Protein Information:calcium-binding mitochondrial carrier protein SCaMC-2; mitochondrial ATP-Mg/Pi carrier protein 3; short calcium-binding mitochondrial carrier 2; small calcium-binding mitochondrial carrier 2; solute carrier family 25, member 25, isoform a; mitochondrial Ca(2+)-dependent solute carrier protein 3
UniProt Protein Name:Calcium-binding mitochondrial carrier protein SCaMC-2
UniProt Synonym Protein Names:Mitochondrial ATP-Mg/Pi carrier protein 3; Mitochondrial Ca(2+)-dependent solute carrier protein 3; Small calcium-binding mitochondrial carrier protein 2; Solute carrier family 25 member 25
Protein Family:Calcium-binding mitochondrial carrier protein
UniProt Gene Name:SLC25A25  
UniProt Entry Name:SCMC2_HUMAN

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