| UniProt Protein Function: | SLC25A21: Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate. Belongs to the mitochondrial carrier family.Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Mitochondrial; Transporter, SLC familyChromosomal Location of Human Ortholog: 14q11.2Cellular Component: mitochondrial inner membrane; integral to membraneBiological Process: lysine catabolic process; transmembrane transport |
| UniProt Protein Details: | |
| NCBI Summary: | SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004] |
| UniProt Code: | Q9BQT8 |
| NCBI GenInfo Identifier: | 283837920 |
| NCBI Gene ID: | 89874 |
| NCBI Accession: | NP_001164641.1 |
| UniProt Secondary Accession: | Q9BQT8 |
| UniProt Related Accession: | Q9BQT8 |
| Molecular Weight: | |
| NCBI Full Name: | mitochondrial 2-oxodicarboxylate carrier isoform 2 |
| NCBI Synonym Full Names: | solute carrier family 25 member 21 |
| NCBI Official Symbol: | SLC25A21Â Â |
| NCBI Official Synonym Symbols: | ODC; ODC1Â Â |
| NCBI Protein Information: | mitochondrial 2-oxodicarboxylate carrier |
| UniProt Protein Name: | Mitochondrial 2-oxodicarboxylate carrier |
| UniProt Synonym Protein Names: | Solute carrier family 25 member 21 |
| Protein Family: | Probable ornithine decarboxylase |
| UniProt Gene Name: | SLC25A21Â Â |
| UniProt Entry Name: | ODC_HUMAN |
