The SLC25A20 Monoclonal Antibody is a valuable tool for research involving SLC25A20, a protein responsible for transporting carnitine across the mitochondrial membrane for fatty acid oxidation. This antibody, produced using hybridoma technology, specifically targets the SLC25A20 protein and is suitable for use in Western blot and immunohistochemistry applications. Its high specificity and sensitivity make it an excellent choice for studying the role of SLC25A20 in metabolism, energy production, and mitochondrial function.SLC25A20, also known as the carnitine/acylcarnitine translocase, is essential for maintaining cellular energy balance and proper functioning of mitochondria.
Dysregulation of SLC25A20 has been linked to metabolic disorders, neurodegenerative diseases, and cardiac dysfunction. Research into the function and regulation of SLC25A20 is important for developing therapies targeting mitochondrial dysfunction and metabolic disorders.The SLC25A20 Monoclonal Antibody is a reliable tool for investigating the function of SLC25A20 in various cell types and tissues, providing valuable insights into its role in health and disease. Its use in research related to metabolism, energy metabolism, and mitochondrial function makes it an essential reagent for scientists studying the molecular mechanisms underlying these processes.
Product Name:
SLC25A20 Monoclonal Antibody
SKU:
CAB23763
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthesized peptide derived from human SLC25A20.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
SLC25A20; CAC; CACT; solute carrier family 25 member 20
This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
Purification Method:
Affinity purification
Gene ID:
788
Clone Number:
ARC59015
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse lung, using SLC25A20 Rabbit mAb (CAB23763) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
