The SLC25A17 Polyclonal Antibody (CAB14840) is designed for research involving SLC25A17, a mitochondrial transporter protein known to play a role in various cellular processes, including metabolism and energy production. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SLC25A17 protein, this antibody allows for the detection and analysis of SLC25A17 in different cell types, making it an ideal tool for studies in mitochondrial biology and metabolic disorders.SLC25A17, also known as the mitochondrial thiamine pyrophosphate carrier, is essential for the transport of thiamine pyrophosphate (TPP) into the mitochondria, where it is crucial for multiple enzymatic reactions involved in energy metabolism.
Dysregulation of SLC25A17 has been linked to various metabolic disorders, making it a potential target for research into conditions such as diabetes, obesity, and neurodegenerative diseases. Understanding the function of SLC25A17 is critical for developing interventions that target mitochondrial dysfunction and metabolic imbalances associated with these diseases.
Product Name:
SLC25A17 Rabbit Polyclonal Antibody
SKU:
CAB14840
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC25A17 (NP_006349.1).
This gene encodes a peroxisomal membrane protein that belongs to the family of mitochondrial solute carriers. It is expressed in the liver, and is likely involved in transport. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10478
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC25A17 Rabbit pAb (CAB14840) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
