The SLC25A14 Polyclonal Antibody (CAB13731) is a valuable tool for researchers studying the SLC25A14 protein, a member of the mitochondrial carrier family. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the SLC25A14 protein, this antibody allows for the detection and analysis of SLC25A14 in various cell types, making it ideal for studies in mitochondrial biology and metabolism research.
SLC25A14 plays a crucial role in transporting metabolites across the inner mitochondrial membrane, contributing to energy production and cellular metabolism. Dysregulation of SLC25A14 has been implicated in various metabolic disorders, making it a promising target for therapeutic intervention. Understanding the function and regulation of SLC25A14 is essential for advancing research in areas such as metabolic diseases, mitochondrial dysfunction, and cancer metabolism.
Product Name:
SLC25A14 Rabbit Polyclonal Antibody
SKU:
CAB13731
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-200 of human SLC25A14 (NP_001269124.1).
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4.
Purification Method:
Affinity purification
Gene ID:
9016
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC25A14 Rabbit pAb (CAB13731) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (AbGn00020)._Exposure time: 90s.
