The SLC25A13 Polyclonal Antibody (CAB12557) is a valuable tool for researchers studying SLC25A13, a mitochondrial solute carrier protein involved in the transport of metabolites across the inner mitochondrial membrane. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SLC25A13 protein, this antibody enables researchers to detect and analyze the expression of SLC25A13 in a variety of cell types, making it an ideal choice for studies in metabolism, mitochondrial function, and related diseases.SLC25A13 plays a crucial role in maintaining mitochondrial function and energy metabolism, making it a key target for research into metabolic disorders, liver diseases, and other conditions associated with mitochondrial dysfunction.
By studying the expression and function of SLC25A13, researchers can gain valuable insights into the mechanisms underlying these diseases and identify potential therapeutic targets for intervention.Overall, the SLC25A13 Polyclonal Antibody is a powerful tool for researchers seeking to explore the role of SLC25A13 in health and disease. Its specificity, sensitivity, and versatility make it a valuable asset for studies investigating mitochondrial function, metabolic pathways, and the pathogenesis of mitochondrial-related disorders.
Product Name:
SLC25A13 Rabbit Polyclonal Antibody
SKU:
CAB12557
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SLC25A13 (NP_001153682.1).
This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10165
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SLC25A13 antibody (CAB12557) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
