The SLC25A12 Polyclonal Antibody (CAB11688) is a powerful tool for researchers studying the SLC25A12 protein, also known as the mitochondrial aspartate/glutamate carrier. This antibody is produced in rabbits and has been validated for use in Western blot applications with human samples. By binding specifically to the SLC25A12 protein, this antibody allows for accurate detection and analysis of this important mitochondrial transporter in various cell types.SLC25A12 plays a key role in transporting aspartate and glutamate across the inner mitochondrial membrane, essential for maintaining cellular energy metabolism and neurotransmitter synthesis.
Dysregulation of SLC25A12 has been linked to neurological disorders, metabolic diseases, and certain types of cancer, making it a promising target for further research.With its high reactivity and specificity, the SLC25A12 Polyclonal Antibody (CAB11688) is an invaluable tool for investigating the function and regulation of SLC25A12 in the context of mitochondrial biology, metabolism, and disease. Its use in immunology and cancer research can potentially lead to a better understanding of pathophysiological mechanisms and the development of new therapeutic strategies targeting SLC25A12.
Product Name:
SLC25A12 Rabbit Polyclonal Antibody
SKU:
CAB11688
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SLC25A12 (NP_003696.2).
This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
8604
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC25A12 Rabbit pAb (CAB11688) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
