The SLC25A11 Polyclonal Antibody (CAB8163) is a valuable tool for researchers studying the SLC25A11 protein, a member of the mitochondrial carrier family involved in transporting metabolites across the inner mitochondrial membrane. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications.SLC25A11 plays a crucial role in cellular metabolism, particularly in the transport of metabolites such as citrate and isocitrate into the mitochondria for energy production. Dysregulation of SLC25A11 has been linked to various metabolic disorders and diseases, making it a promising target for therapeutic interventions.
By using the SLC25A11 Polyclonal Antibody, researchers can accurately detect and analyze SLC25A11 expression in various cell types, gaining insights into its functions in mitochondrial metabolism and its potential implications in diseases such as cancer, diabetes, and neurodegenerative disorders. This antibody is a valuable tool for advancing our understanding of SLC25A11 biology and exploring its therapeutic potential.
Product Name:
SLC25A11 Rabbit Polyclonal Antibody
SKU:
CAB8163
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC25A11 (NP_003553.2).
The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids (summary by Iacobazzi et al., 1992 [PubMed 1457818]).
Purification Method:
Affinity purification
Gene ID:
8402
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC25A11 Rabbit pAb (CAB8163) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
