The SLC22A8 Polyclonal Antibody (CAB14575) is a valuable tool for researchers studying SLC22A8, a cell surface transporter involved in drug uptake and elimination processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By specifically binding to the SLC22A8 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential reagent for studies in pharmacology and drug metabolism.SLC22A8, also known as organic cation transporter 3 (OCT3), plays a crucial role in the transport of endogenous compounds and a wide range of pharmacological agents.
Understanding the function and regulation of SLC22A8 is essential for predicting drug interactions, optimizing drug dosing, and developing personalized medicine approaches. This antibody provides a reliable tool for investigating the expression and localization of SLC22A8 in different tissues, contributing to advancements in precision medicine and drug development.
Product Name:
SLC22A8 Rabbit Polyclonal Antibody
SKU:
CAB14575
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human OAT3/SLC22A8 (NP_004245.2).
This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
9376
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse kidney, using OAT3/SLC22A8 Rabbit pAb antibody (CAB14575) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
