The SLC22A7 Polyclonal Antibody (CAB15137) is a crucial tool for researchers studying SLC22A7, a cell surface transporter protein involved in the uptake and efflux of organic cations. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the SLC22A7 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for investigations in pharmacology, toxicology, and drug metabolism studies.SLC22A7, also known as the solute carrier family 22 member 7, plays a significant role in the transport of endogenous and exogenous compounds across cell membranes, impacting drug absorption, distribution, and excretion.
Understanding the function and regulation of SLC22A7 is essential for advancing research on drug-drug interactions, pharmacokinetics, and personalized medicine. The SLC22A7 Polyclonal Antibody is a valuable tool for unraveling the complexities of SLC22A7-mediated transport processes and their implications in various physiological and pathological conditions.
Product Name:
SLC22A7 Rabbit Polyclonal Antibody
SKU:
CAB15137
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-142 of human SLC22A7 (NP_696961.2).
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
10864
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC22A7 Rabbit pAb (CAB15137) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
